Sharp AR-M236 (serv.man95) Regulatory Data ▷ View online
MATERIAL SAFETY DATA SHEET
Page : 4/5
Date Revised : Jul. 15, 2005
Date Issued : Apr. 2, 2001
MSDS No. F-30981
Date Issued : Apr. 2, 2001
MSDS No. F-30981
11.TOXICOLOGICAL INFORMATION
Acute Toxicity
Ingestion(oral) :
LD
50
> 2500mg/kg (Rats)
Inhalation
: No data
Dermal : No data
Eye irritation
Eye irritation
: Not an irritant (Rabbits)
Skin irritation
: Not an irritant (Rabbits)
Skin sensitizer
: No sensitization
Mutagenicity : Negative (Ames Test)
Carcinogenicity : In 1996 the IARC reevaluated carbon black as a Group 2B carcinogen (possible human
Carcinogenicity : In 1996 the IARC reevaluated carbon black as a Group 2B carcinogen (possible human
carcinogen). This classification is given to chemicals for which there is inadequate human
evidence, but sufficient animal evidence on which to base an opinion of carcinogenicity. The
classification is based upon the development of lung tumors in rats receiving chronic inhalation
exposures to free carbon black at levels that induce particle overload of the lung. Studies
performed in animal models other than rats did not show any association between carbon black
and lung tumors. Moreover, a two-year cancer bioassay using a typical toner preparation
containing carbon black demonstrated no association between toner exposure and tumor
development in rats.
evidence, but sufficient animal evidence on which to base an opinion of carcinogenicity. The
classification is based upon the development of lung tumors in rats receiving chronic inhalation
exposures to free carbon black at levels that induce particle overload of the lung. Studies
performed in animal models other than rats did not show any association between carbon black
and lung tumors. Moreover, a two-year cancer bioassay using a typical toner preparation
containing carbon black demonstrated no association between toner exposure and tumor
development in rats.
Chronic Effect
: In a study in rats of chronic inhalation exposure to a typical toner, a mild to moderate degree of
lung fibrosis was observed in 92% of the rats in the high concentration (16mg/m
3
) exposure
group, and a minimal to mild degree of fibrosis was noted in 22% of the animals in the middle
(4mg/m
(4mg/m
3
) exposure group, but no pulmonary change was reported in the lowest (1mg/m
3
)
exposure group, the most relevant level to potential human exposures.
12.ECOLOGICAL INFORMATION
No data are available.
13.DISPOSAL CONSIDERATIONS
Waste from Residues
: Waste material may be dumped or incinerated under conditions which meet all federal,
state and local environmental regulations.
Contaminated Packaging : Waste may be disposed or incinerated under conditions which meet all federal, state
and local environmental regulations.
14.TRANSPORT INFORMATION
UN Classification
: None
Not classified as hazardous for transport.
15.REGULATORY INFORMATION
US Information
TSCA(Toxic Substances Control Act) :
All chemical substances in this product comply with all applicable rules or order under TSCA.
SARA(Superfund Amendments and Reauthorization Act) Title III
302 Extreme Hazardous Substance : None
311/312 Hazard Classification
311/312 Hazard Classification
: None
EU Information
1999/45/EC and 67/548/EEC
Symbol & Indication
: Not required
MATERIAL SAFETY DATA SHEET
Page : 5/5
Date Revised : Jul. 15, 2005
Date Issued : Apr. 2, 2001
MSDS No. F-30981
Date Issued : Apr. 2, 2001
MSDS No. F-30981
R-Phrase
: Not required
76/769/EEC
: All chemical substances in this product comply with all applicable rules or
order under 76/769/EEC.
16.OTHER INFORMATION
NFPA Rating (USA)
: Health=1
Flammability=1 Reactivity=0
WHMIS Legislation (Canada) : This product is not a controlled product.
References
References
IARC(1996) : IARC monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 65,
Printing Process And Printing Inks, Carbon Black and Some Nitro Compounds, Lyon, pp.149-261
H.Muhle, B.Bellmann, O.Creutzenberg, C.Dasenbrock, H.Ernst, R.Kilpper, J.C.MacKenzie, P.Morrow, U.Mohr,
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
The information on this data sheet represents our current data and best opinion as to the proper use in handling of this
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.
MATERIAL SAFETY DATA SHEET
Page : 5/5
Date Revised : Jul. 15, 2005
Date Issued : Apr. 2, 2001
MSDS No. F-30981
Date Issued : Apr. 2, 2001
MSDS No. F-30981
R-Phrase
: Not required
76/769/EEC
: All chemical substances in this product comply with all applicable rules or
order under 76/769/EEC.
16.OTHER INFORMATION
NFPA Rating (USA)
: Health=1
Flammability=1 Reactivity=0
WHMIS Legislation (Canada) : This product is not a controlled product.
References
References
IARC(1996) : IARC monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 65,
Printing Process And Printing Inks, Carbon Black and Some Nitro Compounds, Lyon, pp.149-261
H.Muhle, B.Bellmann, O.Creutzenberg, C.Dasenbrock, H.Ernst, R.Kilpper, J.C.MacKenzie, P.Morrow, U.Mohr,
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
The information on this data sheet represents our current data and best opinion as to the proper use in handling of this
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.
MATERIAL SAFETY DATA SHEET
Page : 5/5
Date Revised : Jul. 15, 2005
Date Issued : Apr. 2, 2001
MSDS No. F-30981
Date Issued : Apr. 2, 2001
MSDS No. F-30981
R-Phrase
: Not required
76/769/EEC
: All chemical substances in this product comply with all applicable rules or
order under 76/769/EEC.
16.OTHER INFORMATION
NFPA Rating (USA)
: Health=1
Flammability=1 Reactivity=0
WHMIS Legislation (Canada) : This product is not a controlled product.
References
References
IARC(1996) : IARC monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol. 65,
Printing Process And Printing Inks, Carbon Black and Some Nitro Compounds, Lyon, pp.149-261
H.Muhle, B.Bellmann, O.Creutzenberg, C.Dasenbrock, H.Ernst, R.Kilpper, J.C.MacKenzie, P.Morrow, U.Mohr,
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
S.Takenaka, and R.Mermelstein(1991) Pulmonary Response to Toner upon Chronic Inhalation Exposure in Rats.
Fundamental and Applied Toxicology 17, pp.280-299.
The information on this data sheet represents our current data and best opinion as to the proper use in handling of this
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.
product under normal conditions. However, all materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we do not guarantee that these are the only hazards which
exist.
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